If you are staying in Tel-Aviv and wish to conduct a single day tour with emphasis on ancient and modern Jewish history this is my best recommendation:
After Latrun we get off the highway and join the 1948 “Burma Road” “, learning about the battles around Jerusalem in 1948.
Upon reaching Jerusalem we park the car, and head to a tour by foot of the Jewish Quarter , the Western wall , and the visitors center of the “City of David “. These sites presents best the core of Jewish history from the time of King David, to our days. The tour could include a walk in “Hezekiah’s Tunnel “, or joining a tour of the “Western Wall tunnels “.